Study Examines How Social Determinants Influence Cardiovascular Risk for People with Systemic Lupus Erythematosus

Both systemic lupus erythematosus (SLE) and cardiovascular disease (CVD) have disparities related to gender, race and other social determinants that are connected to health outcomes and trajectories. In a new Lupus Science & Medicinestudy, researchers investigated biological, psychological and social factors that influence the development of CVD in people with SLE. 

Researchers reviewed existing literature on SLE, CVD and social factors and identified five main themes that connected CVD risk for those with SLE, including socioeconomic status and education, race and ethnicity, mental health, gender and healthcare quality and/or insurance. Those at highest risk for CVD with SLE had low income, low education, were of Black race and/or ethnicity, had depression, were male, lacked insurance coverage, and received care at multiple institutions/from multiple providers. However, researchers noted that there are gaps with other social determinants as they remain either unexplored or underexplored. Other social determinants include stress, early life, social exclusion, work, unemployment, social support, substance use, food security, transportation, housing, political conflict and health services access. 

This research highlights how various factors interact to influence health outcomes and trajectories. Further research is needed to understand risk factors of CVD, along with things individuals and healthcare providers should monitor for. Learn more about health disparities and social determinants of health.

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