Risk of Adverse Cardiac Events After Surgery in People with Lupus
New research finds people with lupus are at higher risk of experiencing a major negative or adverse cardiac event (heart attack, stroke or death) after undergoing a noncardiac surgery. Additionally, those at high-risk and with lupus received less heart testing 2 months prior to surgery than other groups which is worrisome.
The surgical records of 4,750 people with lupus with and without diabetes, and which had undergone a noncardiac surgery were examined. Having diabetes is already recognized as a major risk for postoperative major adverse cardiac events (MACE) after noncardiac surgery. Those with lupus and diabetes had a significant increase in MACE. The risk of MACE in those with lupus was 1% and 1.5% at 1 and 3 months, respectively.
Those without diabetes and lupus also saw significant increases in MACE at 1 month (49%) and at 3 months (83%). The increase of MACE in those with lupus is likely due to increased presence of comorbidities and cardiovascular disease in those with the condition. Further research into pre- and post-surgical care in people with lupus is needed to better manage risk and curtail negative outcomes. Learn more about how lupus affects the heart.
Interested in getting research like this straight to your inbox? Subscribe to our bimonthly Inside Lupus Research email for all the latest.Subscribe Now