New Study Uncovers Information about Lupus Subgroups
Lupus is a heterogeneous (diverse) disease. People with lupus look different both molecularly (at the cell level) and clinically. And, because of this, can be broken down into subgroups. Recent research has shed light on the fact that the differences in these subgroups may impact treatment response and clinical trial outcomes.
A new research study isolated people with lupus into two subgroups so they could identify key differences. Researchers studied two of the subsets (those with antiphospholipid antibodies and those with antibodies present in Sjögren’s syndrome) to better understand how their molecular profiles play a role in their response to treatments. Results from this study showed that stratifying (dividing) people with lupus based on their molecular profile could potentially improve future clinical trials and treatment response. Learn more about lupus.