The Purple Ball is the signature gala benefiting the Lupus Foundation of America, Heartland Region, bringing together community leaders, healthcare professionals, advocates, and supporters for an unforgettable evening of purpose and celebration. Each year, this elegant event lights up the night in shades of purple—the color of lupus awareness—as we honor those making extraordinary strides in the fight against lupus. 

This year’s Purple Ball will be held on May 1, 2026 at the Four Seasons St. Louis, featuring a cocktail reception, fine dining, inspiring program, and entertainment. Guests will enjoy a night filled with connection, compassion, and commitment to advancing lupus research, support, and advocacy.