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Biogen Inc. announced today that its Phase 2 LILAC study captured positive top-line results for investigational drug, BIIB059. The drug demonstrated statistically significant reduction of disease activity in people with cutaneous lupus (CLE) and systemic lupus erythematosus (SLE) compared to those who received placebo.
The drug is a monoclonal antibody that blocks BDCA2 cells which inhibit the production of major inflammatory mediators in lupus. The Phase 2 LILAC study was a two-part, randomized, double blind, placebo-controlled study that enrolled 264 individuals. The safety and tolerability profile of BIIB059 supports its continued development. The drug continues to be researched in SLE and CLE.
BIIB059 shows promise as a new treatment option. Continue to follow the Lupus Foundation of America for updates on BIIB059 and learn more about medications used to treat lupus.
Lupus Foundation of America, Greater Ohio Chapter
12930 Chippewa Road
Brecksville, OH 44141
Join us September 16 for our free Lupus & You webinar about workplace accommodations and Social Security Disability Insurance (SSDI) for people with lupus.
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