Distinguishing between infection and systemic lupus erythematosus (SLE) is difficult, as each produces similar symptoms. Infections and lupus disease activity, or flares, require different treatments, so the correct diagnosis is critical. A new study has found that the neutrophil-to-lymphocyte ratio (NLR) plus C-reactive protein (CRP) could also be an additional biomarker, or measurable indicator, when non-viral infection is suspected in people with lupus. CRP is commonly used to measure lupus disease activity. NLR also measures inflammation but is not commonly used. The Lupus Foundation of America will continue to monitor the progress of biomarkers which may help in the management of lupus.

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