Dr. Joseph McCune of the University of Michigan discusses the role interferon and endothelial cells, which line blood vessels, as possible causes of increased risk of heart attacks and strokes associated with lupus.
Congenital Heart Block in Neonatal Lupus
Although very rare, newborns of women with lupus are at greater risk for developing a potentially life-threatening complication known as congenital heart block. Dr. Jill Buyon of the New York University School of Medicine is a leading authority on this complication of lupus. Dr. Buyon discusses her life-long effort to study this complication and shares what has been learned and the next steps in the study of neonatal lupus.
Dr. Kathleen O'Neil discusses a multi-center longitudinal observational study of girls with prepubertal onset lupus as they approach and pass through puberty, measuring hormone levels, autoantibodies and markers of lupus activity.