Lupus and your body

What is antiphospholipid antibody syndrome (APS)?

Dr. Michelle Petri is the Director of the Hopkins Lupus Cohort, a longitudinal study of morbidity and mortality in systemic lupus erythematosus, and Co-Director of the Hopkins Lupus Pregnancy Center.

See all of Michelle Petri, MD, MPH's answers.

Antiphospholipid antibodies have been found to be increased in pregnant women with or without lupus who have had miscarriages. The combination of thrombotic problems, miscarriages, and/or a low platelet count has been called the “antiphospholipid antibody syndrome (APS).” It is not necessary to have lupus to have the antiphospholipid antibody syndrome. It is important for doctors to realize this and to check people who have had a stroke, heart attack, or miscarriage for no known reason, to see if they have these antibodies.

Medically reviewed on July 26, 2013