Skip to main content

Understanding Lupus

Lupus is a cruel mystery we must all solve together

Lupus is an unpredictable and misunderstood autoimmune disease that ravages different parts of the body. It is difficult to diagnose, hard to live with, and a challenge to treat. Lupus is a cruel mystery because it's hidden from view and undefined, has a range of symptoms, and strikes without warning, and has no known cause or cure

6 years

is the average time from the onset of symptoms to obtaining a diagnosis of lupus


is the average annual financial impact of lupus, per person


people list chronic pain as the most difficult aspect of lupus

Dan B.
I feel like I’m in safe place where I can talk about my experience with people who know how I feel, what I’m going through.
Signs & Symptoms
Lupus can affect any organ system in the body

The impact of lupus ranges from mild to life-threatening

Symptoms often mimic those of other less serious diseases

Joint pain, skin rashes, fevers and fatigue are most common

Lupus symptoms can be vague and come and go over time

Diagnosis is difficult because lupus disease activity often is unpredictable

Impact on Daily Life

Alt text

Having lupus can make everyday life challenging. When your lupus is active, symptoms like joint stiffness, pain, fatigue, confusion, or depression can make simple tasks difficult — and sometimes impossible. However, there are steps you can take to stay involved with work, relationships, and the activities you care about.

Learn how lupus affects daily life

Play Video
"It started with a rash"

Maurissa Tancharoen Whedon shares her journey with lupus in this brief video about the need to find a cure for this unpredictable, misunderstood autoimmune disease.

How lupus is diagnosed
Treating Lupus
Providing an Arsenal of Treatments

No two lupus patients are identical, so multiple treatments are needed to manage the spectrum of disease

Developing New Targeted Therapies

Behind every new treatment is an army of volunteers who participate in lupus clinical research studies

Funding Research for Tomorrow’s Cures

We spearhead efforts to advance lupus drug development at every step in the process

Help accelerate the search for cures

We were the first organization to fund lupus research, and we have driven every major milestone since. Join our efforts to help researchers find effective treatments and a cure for lupus.

Donate Now