Jul. 01, 2014

Duke University Lupus Researcher among New Generation of Investigators

Lupus Foundation of America Announces Recipients of its 2014 National Lupus Research Program Career Development Award and Summer Student Fellowships

(July 1, 2014; Washington, DC) – The Lupus Foundation of America has announced that Laura Lewandowski, M.D., Duke University Medical Center, Durham, North Carolina, is the 2014 recipient of the Foundation’s Career Development Award.   Dr. Lewandowski receives the award to support her lupus research project entitled, PULSE: Pediatric Update on Lupus in South Africa: Epidemiology & Management.  Laura E. Schanberg, M.D., a pediatric rheumatology specialist with Duke Medicine, will serve as Lewandowski’s mentor for the project.  

Now in its second year, the Foundation’s Career Development Award supports the field of lupus research at a time when public and private funding opportunities are increasingly more challenging to secure, and when individuals in the early part of their careers must make critical decisions about their future paths. The Foundation created this award to facilitate the professional development of rheumatology, nephrology and dermatology fellows who are interested in careers as clinician-scientists at institutions that have a research program with a substantial focus on lupus. The award supports the work of these fellows as they transition from training to independent careers.

In addition to the Career Development Award, the Lupus Foundation of America, the only national force dedicated to solving the cruel mystery of lupus, announced that six doctoral students were selected as the 2014 recipients of the Gina M. Finzi Memorial Student Summer Fellowship. This one-of-its-kind fellowship program was established more than 25 years ago by former Lupus Foundation of America President, the late Dr. Sergio Finzi, in memory of his daughter Gina, who passed away from lupus. The program seeks to cultivate an interest in lupus research among young scientists by funding basic, clinical, translational, epidemiological and behavioral lupus research studies, conducted under the supervision of an established investigator.

The six young scientists, chosen through a rigorous review process, were awarded fellowships to pursue research efforts in lupus. Their studies will focus on important topics, such as the influence of genetics on the manifestation of lupus, the relationship between platelets bearing complement activation product C4d (PC4d) and cardiovascular disease, lupus nephritis, B-cells  and the roles of the MAVS-inhibitory protein NLRX1, retinaldehyde and adipogenesis in lupus.

The 2014 recipients include:

  • Milena Gianfrancesco, University of California (Berkeley), Berkeley, CA
    Mentor: Lindsey Criswell, M.D., M.P.H.
    Project title: Causal Inference Approach to Study Disease Activity in Lupus
  • Jennifer Mall, Allegheny-Singer Research Institute, Pittsburgh, PA
    Mentor: Joseph Ahearn, M.D.
    Project Title: CVD Risk Factors and Events in the Pittsburgh Lupus Cohort Over 20 Years
  • Laura Plantinga, Emory University, Atlanta, GA
    Mentor: S. Sam Lim, M.D., M.P.H.
    Project title: End-stage Renal Disease Incidence Among Newly Diagnosed SLE Patients
  • Priti Prasad, University of California (Los Angeles), Los Angeles, CA
    Mentor: Ram Raj Singh, M.D.
    Project Title: Analysis of Innate B cells in a Model of Chemically-induced Pulmonary Lupus
  • Daniel Shu, Temple University, Philadelphia, Pennsylvania
    Mentor: Philip L. Cohen, M.D.
    Project Title: Expression of MAVS-inhibitory Protein NLRX1 in Systemic Lupus Erythematosus
  • Shi Su, Boston University, Boston, MA
    Mentor: Tamar Aprahamian, Ph.D.
    Project Title: The Role of Retinaldehyde and Adipogenesis in Systemic Lupus Erythematosus

These young scientists join the ranks of more than 200 Finzi Student Fellows that the Foundation has supported since the program’s inception. The partnership between student and established investigator is an important component of this unique program. Recipients of this valued fellowship have produced numerous papers that have been published in respected peer-reviewed journals, earned M.D. and Ph.D. degrees, and become medical practitioners and academic researchers.

“The Lupus Foundation of America is thrilled to welcome this year’s award recipients into its National Research Program to stimulate their interest in helping to solve this unpredictable and misunderstood disease,” explains Graciela S. Alarcón, M.D., M.P.H., Emeritus Jane Knight Lowe Chair of Medicine, University of Alabama, Birmingham and Member of the Lupus Foundation of America’s Medical-Scientific Advisory Council. “Our hope is that the efforts of these young scientists will advance our understanding of lupus and lead to the next breakthrough in lupus research.”

More information about the Lupus Foundation of America’s National Research Program is available online at lupus.org/research.

About Lupus:
Lupus is an unpredictable and misunderstood autoimmune disease that ravages different parts of the body. It is difficult to diagnose, hard to live with, and a challenge to treat. Lupus is a cruel mystery because it is hidden from view and undefined, has a range of symptoms, hits out of nowhere, and has no known cause and no known cure. Its health effects can range from a skin rash to a heart attack. Lupus is debilitating and destructive, and can be fatal, yet research on lupus remains underfunded relative to its scope and devastation.

About the Lupus Foundation of America, North Carolina Chapter:
The Lupus Foundation of America, North Carolina Chapter is part of the national force devoted to solving the cruel mystery of lupus while providing caring support to those who suffer from its brutal impact. We work with local health professionals and volunteers to provide information and programs to ensure people with lupus and their families get answers and health professionals know about new means to diagnose and manage the disease. The chapter serves an estimated 45,000 living with lupus in North Carolina.  For more information about lupus or the LFANC, visit www.lupusnc.org or call (877) 849-8271. For the latest news and updates, follow us on Facebook and Twitter.

About the Lupus Foundation of America Peer Reviewed Research Program:
The Lupus Foundation of America is dedicated to addressing scientific issues that have obstructed basic, clinical, epidemiological, behavioral and translational lupus research for decades. Our research grant program focuses its support in areas of research where significant gaps in scientific knowledge about lupus exist, and where other public and private organizations are not focusing their efforts. The program supports growth in the field during a time when federal government funding opportunities are limited. Through our peer reviewed lupus research program, the Foundation directly funds lupus investigators to conduct studies in areas identified by our Medical-Scientific Advisory Council (MSAC).

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