Dr. William Stohl of the University of Southern California discusses the relationships among various parts of the immune system and their role in triggering lupus.
Perspectives on B-cell Research in Lupus
The immune system is made up of many different cells, each with a specific role to play. In lupus, the immune system is out of balance causing the immune system to produce autoantibodies directed at the body's own tissue. The question for lupus researchers is why these autoantibodies are present and why they are are targeting 'self.' Dr. Gregg Silverman is head of the Laboratory of B-cell Immunology at the University of California, San Diego. He and his lab have been studying B-cells and how they contribute to the development of lupus. In this video he discusses his work and offers insight on the current status and future direction of lupus research.
Dr. David Pisetsky of Duke University Medical Center discusses the role of apoptosis (programmed cell death) and microparticles in triggering lupus.