Dr. Jill Buyon of the New York University School of Medicine, a leading authority on congenital heart block in neonatal lupus, discusses this rare complication and the next steps in the study of neonatal lupus.
Effect of Pubertal Hormone Changes on Lupus
Lupus in childhood usually attacks children as they enter puberty. Hormones change in an orderly pattern during puberty, making the study of lupus in this period of life ideal to understand how hormones affect autoimmunity and disease activity in lupus. Dr. Kathleen O'Neil received a Lupus Foundation of America national research program grant to support a multi-center longitudinal observational study of girls with prepubertal onset lupus as they approach and pass through puberty, measuring hormone levels, autoantibodies and markers of lupus activity. In this video, Dr. O'Neil discusses the objectives of the study, the potential benefits in our understanding of lupus, and how in the future the disease might be treated and controlled in children.
Dr. Emily Von Scheven, Director of Pediatric Rheumatology at the University of California San Francisco Medical Center, discusses the issues surrounding bone health in children with lupus and other health issues associated with treatment of lupus.