Neuropsychiatric Lupus (NPSLE) Research

Neuropsychiatric lupus (NPSLE) refers to lupus that affects the central or peripheral nervous system. NPSLE affects the quality of life for a large percentage of people with lupus. The most common signs and symptoms of this condition include cognitive dysfunction (sometimes called lupus fog), headache, mood and anxiety disorders, cerebrovascular disease, seizure or seizure disorders, and neuropathy. Both neurologic and psychiatric abnormalities appear in forms that may be subtle but sufficient to change a person’s lifestyle and lead to disability. The Foundation is supporting studies whose basic, clinical, or translational research outcomes will significantly enhance our current understanding of common manifestations of NPSLE in adult and pediatric populations. Learn more about LFA funded neuropsychiatric lupus research.