Lupus Nephritis Research

Lupus-related kidney disease, called lupus nephritis, is a very serious complication of lupus. If lupus nephritis is not treated successfully, it can lead to kidney damage, organ failure, which may require dialysis several times a week, a kidney transplant or even death. Approximately 25 to 60 percent of people with lupus will have their kidneys affected, with the highest risk among African Americans and Hispanics with a high Amerindian background.

Despite advances in treatment, some people with lupus nephritis continue to have progressive loss of kidney function. Researchers must determine the underlying causes of this life-threatening form of lupus to improve treatment and health outcomes.  The Foundation is stepping up its efforts to support studies in this urgent area of lupus research. Learn more about LFA funded lupus nephritis research.