Lupus Nephritis Research

Lupus nephritis, which can damage and scar the kidneys and other parts of the renal system, is one of the most common and serious complications of lupus. Between 50 and 60 percent of people with lupus will develop lupus nephritis within 10 years of their lupus diagnosis, and the rate is even higher among children with the disease. Lupus nephritis is more prevalent in African Americans and Hispanics than in Caucasians, and develops more often in males than in females. If not adequately controlled, lupus nephritis can lead to kidney failure, the need for chronic dialysis or kidney transplantation, and potentially death.

Our Approach and Focus

We continue to break new ground by funding research to better understand lupus nephritis in both children and adults. We have awarded numerous grants to leading investigators whose lupus nephritis studies have the potential to lead to the next breakthrough in the field. For example:

  • Assessment of side effects of drugs being used to treat lupus nephritis
  • Development and implementation of specialized treatment guidelines, innovative health care delivery models, and quality of life measures
  • Development of new blood tests to improve the tracking of lupus nephritis in children
  • Evaluation of the role of genetics in response to lupus nephritis treatment outcomes
  • Identification and characterization of biomarkers that indicate lupus nephritis existence, disease activity, or specific pathologies
  • Research into therapeutic interventions and disease mechanisms of lupus nephritis

Learn more about our funded lupus nephritis research studies.