The researchers hoped to determine whether differences in genetic ancestry and/or specific genes contribute the decreased risk of developing lupus nephritis among individuals of European descent.
The researchers hoped to learn about second pregnancy outcomes in women with lupus, particularly in those whose first pregnancy had an adverse outcome.
People with lupus are at increased risk of cardiovascular disease, especially when taking steroids. The use of anti-malarial drugs, such as hydroxychloroquine, significantly reduces this risk.
The researchers hoped to learn about the relationship between type I interferon and premature heart disease risk among people with lupus.
A more detailed understanding of the reproductive behavior of women with lupus can help identify their needs in terms of caring for their disease and become educated about its possible effects, including those on reproduction.
The use of lupus biomarkers, such as those present in the blood or urine, to help predict and/or manage lupus nephritis over time could be very useful. The results of this study highlight the potential feasibility of using lupus biomarkers to differentiate between acute and chronic kidney disease activity-related changes.
The researchers hoped to learn about the long-term outcomes of bone mass density (BMD) in children newly diagnosed with lupus.
The development of a single test that can simultaneously measure several different autoantibodies important in lupus could be important and useful.