Nov. 09, 2011

Using PDL-1 Molecule to Distinguish Between Flare and Infection

People with lupus have compromised immune systems due to the disease and the immune-suppressing medications required to treat it. It can be difficult for doctors to know whether a patient’s symptoms are due to an infection or a lupus flare. Delayed or inappropriate treatment of either condition can be life-threatening. In a study supported in part by the Lupus Foundation of America, Dr. Anne Stevens of the University of Washington, Seattle Children’s Hospital evaluated the role of a protein found in the blood, called PD-L1, to help determine whether an illness is lupus-related or the result of an infection. Data from this study could lead to a novel biomarker to aid in rapidly determining appropriate treatment for acutely ill lupus patients. 

Presenter: Anne Stevens, MD, PhD

Presentation date: November 9, 2011

Length: 5:45


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