Ask The Experts: Dr. Donald Thomas, author of The Lupus Encyclopedia, provides information about diagnosis of lupus.
Using PDL-1 Molecule to Distinguish Between Flare and Infection
People with lupus have compromised immune systems due to the disease and the immune-suppressing medications required to treat it. It can be difficult for doctors to know whether a patient’s symptoms are due to an infection or a lupus flare. Delayed or inappropriate treatment of either condition can be life-threatening. In a study supported in part by the Lupus Foundation of America, Dr. Anne Stevens of the University of Washington, Seattle Children’s Hospital evaluated the role of a protein found in the blood, called PD-L1, to help determine whether an illness is lupus-related or the result of an infection. Data from this study could lead to a novel biomarker to aid in rapidly determining appropriate treatment for acutely ill lupus patients.
Presenter: Anne Stevens, MD, PhD
Presentation date: November 9, 2011